The soils of Château Prieuré-Lichine are essentially made up of gravel deposited by the river during successive glacial floods in the Quaternary era. Streams resulting from the floods then cut up these sedimentary soils into well drained mounds, which today look out over the Gironde estuary. Château Prieuré-Lichine therefore boasts a unique geological past, making the soils, in more ways than one, particularly representative of the Margaux appellation.

The Margaux appellation encompasses the village of Margaux and the neighbouring villages of Arsac, Labarde, Soussans and Cantenac. Being the most southerly of the Médoc's appellations, it has the thinnest soil in the region with the highest proportion of gravel that allows the soil to drain very well. The wine from this area are very susceptible to weather effects during the growing season. Encountering all seasons with adequate irrigation, relatively good rainfall and good amount of sunlight, the crop yields a bountiful harvest year-on-year. The winery takes pride and value that captures the essence that reflects their unique brand.